Location: 2nd St and Walnut St, Murphysboro Reassurance shield as 13 joins 149/127. Location: 2nd St and Route 149, Murphysboro Less than a mile later, 149 splits to continue east. Location: 2nd St and Route 149, Murphysboro Follow 149 east to Desoto. Stay on 13/127 for Pinckeyville. Location: 2nd St and Route 149, Murphysboro Turn … Continue reading Illinois Route 127, IL-13 to IL-149